Synthesis, Characterization, And Bioactivity Evaluation Of 4-Methoxybenzohydrazide And Its Metal Complexes

19 Sep

Authors: Niranjan Kumar Mandal, Ranjan Kumar

Abstract: A series of 4-methoxybenzohydrazide (H2L) and its Ni(II), Co(II), Cu(II), Pd(II), Mn(II), and Fe(II) metal complexes were synthesized and characterized. The ligand and its metal complexes were obtained in good yields and characterized by various spectroscopic techniques, including FT-IR, 1H NMR, 13C NMR, and mass spectrometry. The coordination mode of the ligand and the geometrical structures of the metal complexes were proposed based on the spectroscopic data. The bioactivity of the ligand and its metal complexes was evaluated, including antimicrobial, antioxidant, and cytotoxicity assays. The results showed that the metal complexes exhibited enhanced bioactivities compared to the free ligand, indicating their potential as therapeutic agents.

DOI: http://doi.org/10.5281/zenodo.17158336