Demographic Variations in Breast Cancer

Authors- Wasi Akbar Rizvi

Abstract-Abstract:Demographic variations in breast cancer refer to the disparities and differences in the occurrence, characteristics, and outcomes of breast cancer across various demographic factors. These factors include age, gender, race, ethnicity, socioeconomic status, and geographic location. Research indicates that breast cancer incidence and mortality rates vary among different demographic groups, highlighting the importance of understanding and addressing these variations. Factors such as genetic predisposition, access to healthcare, lifestyle choices, and environmental influences contribute to the complex interplay of demographics in breast cancer. Efforts to reduce disparities often involve targeted awareness campaigns, improved healthcare access, and tailored interventions to address the unique challenges faced by different demographic populations. Breast cancer poses a significant health challenge in India, characterized by both a high prevalence of triple-negative breast cancer (TNBC) and a low overall survival (OS) rate. The current study aimed to assess the diagnostic trends and prevalence of breast cancer among Indian women treated at major private oncology superspecialty hospitals. Methods. A retrospective study was conducted from January 2010 to December 2016 on 5,688 female patients with primary breast cancer in four hospitals in India. The data were analyzed for breast cancer epidemiology in terms of demographics, ER, PR, and HER2/neu data. TNM staging was used to calculate the survival data, which were available for 2,376 patients. Results. TNBC was observed in 21.6% (629/2913) of the patients. Overall, the study found favorable OS and recurrence-free survival outcomes and were diagnosed at an early stage compared to the non-TNBC group. Conclusions. The study highlights the critical need for comprehensive strategies to enhance the prognosis of Indian women with breast cancer.

DOI: /10.61463/ijset.vol.12.issue2.173