Authors: Tamanna Tandon, Pranay Jain
Abstract: Mucormycosis is a fatal fungal infection caused by filamentous molds belongs to order Mucorales.. Mucormycosis is observed to be more prominent in immunocompromised patients. In certain developed economies, mucormycosis is seen to be an associated infection with a bad prognosis regulated diabetes mellitus (DM). Mucormycosis or commonly known as black fungus, has a strong tendency of invading blood, causing nacrosis, thrombosis, and tissue infraction. Mucormycosis is found to be predisposed in co-morbidity or in the non-diabetic patients of COVID-19 especially in those who were at high dosage of steroids for a longer period of time or on ventilator support. Additionally poor hygienic conditions or disturbed diabetic management provides favorable conditions for the pathogenic fungal infection. Other reasons which are responsible for mucormycosis can be excess of uncontrolled conventional precautions. One of them is regular steaming, which may cause affliction in the nasal tracts’ beneficial microbiota and virome. Early diagnosis is crucial to initiate the therapeutic interventions necessary for preventing progressive tissue invasion and its devastating sequelae, minimizing the effect of disfiguring corrective surgery and improving outcome and survival. In this review, the black fungus causes and cures of Mucormycosis have been highlighted. It contains cases from Mucormycosis outbreak, the pathogenesis and diagnosis of the respective disease along with its available treatments. This review also suggests some natural treatments for black fungus disease.
International Journal of Science, Engineering and Technology