AI-Based CRISPR Guide RNA Design for Viral Genome Editing

12 May
Posted on Author Naveen

AI-Based CRISPR Guide RNA Design for Viral Genome Editing

Authors- Yogesh K

Abstract-– The development of CRISPR-Cas systems has opened new frontiers in genome editing, with applications extending into virology for targeting and disabling viral genomes. A critical component of CRISPR technology is the guide RNA (gRNA), which directs the Cas enzyme to specific genomic loci. The precision and efficiency of viral genome editing depend heavily on the accurate design of these gRNAs. Artificial intelligence (AI) has emerged as a transformative tool in this domain, providing predictive models that enhance the selection of effective gRNA sequences while minimizing off-target risks. This research article explores how AI-based approaches are being integrated into gRNA design pipelines to optimize viral genome editing, particularly in therapeutic contexts.

DOI: /10.61463/ijset.vol.13.issue2.431