International Journal of Science, Engineering and TechnologyAuthors: Karthikeyan D, Sayed neamina S, Senthamizh arasi P, Sivasakthi V
Abstract: This project focuses on the eco-friendly synthesis of iron oxide nanoparticles using Punica granatum peels and their application in advanced drug delivery systems through nanobead formulation. In recent years, nanotechnology has emerged as a powerful tool in biomedical engineering, particularly in improving drug delivery efficiency and reducing side effects. Conventional methods for nanoparticle synthesis involve toxic chemicals, high energy consumption, and environmental hazards. To overcome these limitations, green synthesis using plant-based materials has gained significant attention. Pomegranate peels are rich in bioactive compounds such as polyphenols, flavonoids, and tannins, which act as natural reducing and stabilizing agents in nanoparticle formation. In this study, iron oxide nanoparticles were synthesized using aqueous peel extract and further characterized using UV-Visible spectroscopy and FTIR (Fourier Transform Infrared Spectroscopy) analysis to confirm their formation and functional groups. The synthesized nanoparticles were then incorporated into polymer-based nanobeads using biocompatible materials such as alginate or chitosan. These nanobeads were used as carriers for drug delivery, enabling controlled and sustained release of therapeutic agents. The results demonstrate enhanced drug loading efficiency, improved stability, and reduced toxicity compared to conventional delivery methods. Overall, this project highlights the potential of green nanotechnology in developing safe, cost-effective, and efficient drug delivery systems for biomedical applications.
