International Journal of Science, Engineering and TechnologyAuthors: Sachin Gihar
Abstract: Olefin metathesis has fundamentally restructured retrosynthetic analysis in modern organic chemistry [cite: 2, 7]. By exploiting the reversible cleavage and reformation of carbon-carbon double bonds via a metal-carbene intermediate, complex molecular architectures can be assembled with remarkable atom economy [cite: 1, 2]. This comprehensive treatise explores the metathesis phenomenon from its thermodynamic and kinetic underpinnings to its most advanced stereoselective applications [cite: 5, 6]. Detailing the Chauvin mechanism, catalyst evolution, asymmetric desymmetrization, and macromolecular polymerization techniques, this text serves as a definitive resource for post-graduate researchers and advanced synthetic design [cite: 1, 3, 7].
